Urolithin A has rapidly been picking up traction in the supplement world, recognised for its ability to freeze ageing in its tracks by supporting your vitality at a cellular level.
A natural metabolite, Urolithin A is a wonderful little bioactive compound that is produced by the gut when you consume ellagitannins.
Ellagitannins are plant compounds found in foods like pomegranates and nuts – foods missing from many of our diets! This means many of us don’t produce enough Urolithin A naturally.
In fact, many of us can’t produce Urolithin A at all. People without bacteria from the Ruminococcaceae and Clostridiales families in their gut simply cannot make it.
Research suggests that just 40% of people can naturally convert Urolithin A from their diet – and that as little as one in three people can make a sufficient amount!
So why is that a big deal?
Well, once you understand the many benefits of Urolithin A, we’re sure you’ll understand why you don’t want to be missing out.
Urolithin A Benefits – What Are They?
The key role of Urolithin A in the body is to support your mitochondrial health. It does this by stimulating mitophagy, a process which removes and recycles dysfunctional mitochondria.
This allows your cells to stay in tip-top condition, keeping the powerhouses of your cells in proper working order.
As Urolithin A supports the regeneration of your cells across the board, it can support your body in a number of ways.
So, let’s take a look at all the ways Urolithin A could help you!
Reducing Wrinkles
One of Urolithin’s most popular uses is as an anti-ageing supplement: so it’s no wonder that it’s known for its ability to fight wrinkles!
As we age, our body struggles to make the same amount and quality of collagen – resulting in lines and wrinkles in the skin.
This means that helping to support the body’s collagen production can directly counter wrinkly skin, keeping skin plump and youthful in appearance.
Research has shown that Urolithin A at 1% significantly up-regulated collagen synthesis pathways in human skin biopsies.
This helped to significantly reduce the depth of facial wrinkles, while significantly boosting skin hydration. By inhibiting collagen degradation and pro-inflammatory pathways, Urolithin A can help to support younger-looking skin at a cellular level.
Fighting Inflammation
Many of us have come across the idea of inflammation, but don’t have much idea what it actually means for the body.
While inflammation is a natural response – helping the body to react and deal with injuries and invaders – it can be detrimental, with chronic inflammation being a leading cause of age-related issues.
Studies have shown Urolithin A can effectively counteract “inflamm-aging”, exerting a noticeable anti-inflammatory effect across the body. This was noted as UA effectively decreased MRNA, cyclooxygenase, and proinflammatory cytokines, all of which are classic markers of inflammation.
In doing so, Urolithin A has been linked to a number of age-related benefits – including better skeletal muscle function, improved brain function, reduced chance of cardiovascular disease, lower chance of gut problems, and even an improved lifespan!
Protecting Cognitive Function
You might’ve gathered by now that Urolithin A’s benefits aren’t just skin-deep; this magical little compound can help to improve many different areas of your well-being.
Your brain is a sensitive thing, with neurons demanding a high amount of energy and the preservation of your mitochondrial homeostasis, requiring your body to keep up effective mitophagy.
When this doesn’t happen, misfolded proteins known as amyloid plaques can build up in the brain, leading to reduced memory, cognitive function, and even Alzheimer’s disease.
Fortunately, Urolithin A could help to protect your mind.
Studies have shown that (by activating autophagy), UA can help to clear amyloid plaque build-up in the brain, helping to prevent memory loss and the onset of cognitive issues.
Better Muscle Performance
Muscle performance is a concern for people of all ages. We’d all like to feel like we’re fit and healthy, and thankfully, Urolithin A can help you out there too.
Excessive free radicals can stop your muscle cells from working properly, affecting energy production and recovery capacity.
Thanks to its antioxidant properties, Urolithin A is thought to reduce the production of free radicals and protect mitochondria from oxidative stress-induced damage.
This has been shown to have a positive effect on muscle performance and recovery, keeping muscle cells energised to achieve better stamina and strength!
Improved Metabolism
Having a healthy metabolism is important for a lot of reasons. Your metabolism is a series of chemical reactions that create energy by breaking down fat and calories.
Having a good metabolic rate means you’ll feel more energised and, of course, be able to eat more calories. When you have a poor metabolic rate, you may feel more tired, and you’ll put on weight easier.
Your metabolic rate is determined by a few different factors, like genetics, but they generally start to slow down as we age.
Fortunately, Urolithin A may be able to turn the tide.
Research has shown that Urolithin A can trigger the adenosine monophosphate-activated protein kinase (AMPK) signalling pathway, a key regulator of energy metabolism.
UA has also been shown to affect the activity of PPARy, a key transcribing factor involved in both glucose metabolism and cholesterol metabolism.
By up-rating these factors, your metabolic rate could increase, potentially helping to boost your energy – while letting you eat more food and lose more weight!
Urolithin A Side Effects – What Are They?
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While a lot of promising benefits have been discovered relating to Urolithin’s impact on mitochondrial health, no serious side effects have been reported.
In fact, current research shows that Urolithin A is ‘safe and well tolerated’. This means that you should be able to take the supplement long-term without any issues.
With that being said, it’s always good to get your doctor’s advice before adding a supplement to your routine to ensure you avoid any negative interactions with medications you might currently be taking.
Always stick to the recommended dose as stated on the packing – don’t try taking more for more results! We advise that you take one of our 500mg capsules a day with a glass of water.
What Makes a Good Urolithin A Supplement?
When you’re searching for a Urolithin A supplement, it’s important to find a quality, trustworthy product containing an effective dose.
Our pure 500mg Urolithin A supplements are all crafted in the UK to the highest GMP standards, so you know you’re receiving a product you can trust. Each pure-strength capsule features nothing but Urolithin A, so you know you’re not getting any filler or hidden nasties.
We’ve crafted each of our versatile supplement capsules so you can customise how you can take them. You can down them as a capsule, or pop them open to add the powder to meals or smoothies – the choice is yours!
Is Urolithin A Right for Me?
Urolithin A is steadily growing in popularity every day. And it’s no wonder why!
Supporting your mitochondrial health can help you out in a number of ways, helping to fight the signs of ageing and preserve your well-being.
However, with so many nootropics and supplements out there, deciding on the right one for you can feel a bit tricky.
If you need help finding the right fit for you, just head on over to our straightforward supplements quiz! This will take account of your needs and situation, letting you find the perfect solution in just a couple of minutes.
Each of our Fitimins has been formulated and selected by our expert in-house scientists based on hard science and clinical research, so no matter which of our Fitimins you choose, you’re sure to be on the right path to achieving a better sense of well-being.